Graduate Student 2013-2017
After Mo Lab: Research Scientist, Encodia, Inc. (San Diego, CA)
B.S. Chemistry, Mount Holyoke
schramma@princeton.edu
Mo Lab Publications
Schramma, K. R.; Forneris, C. F.; Caruso, A.; Seyedsayamdost, M. R. Mechanistic Investigations of Lysine-Tryptophan Crosslink Formation Catalyzed by Streptococcal Radical SAM Enzymes. Biochemistry 2018, 57, 461-468.
Davis, K. M.; Schramma, K. R.; Hansen, W. A.; Bacik, J. P.; Khare, S. D.; Seyedsayamdost, M. R.; Ando, N. Structures of the Peptide-Modifying Radical SAM Enzyme SuiB Elucidate the Basis of Substrate Recognition. Proc. Natl. Acad. Sci. USA 2017, 114, 10420-10425.
Nazari, B.; Forneris, C. C.; Gibson, M. I.; Moon, K.; Schramma, K. R.; Seyedsayamdost, M. R. Nonomuraea sp. ATCC 55076 Harbours the Largest Actinomycete Chromosome to Date and the Kistamicin Biosynthetic Gene Cluster. Med. Chem. Commun. 2017, 8, 780-788.
Schramma, K. R.; Seyedsayamdost, M. R. Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci. ACS Chem. Biol. 2017, 12, 922-927.
Papenfort, K.; Silpe, J. E.; Schramma, K. R.; Cong, J.-P.; Seyedsayamdost, M. R.; Bassler, B. L. A Vibrio cholerae Autoinducer-Receptor Pair that Controls Biofilm Formation. Nat. Chem. Biol. 2017, 13, 551-557.
Schramma, K. R.*; Bushin, L. B.*; Seyedsayamdost, M. R. Structure and Biosynthesis of a Macrocyclic Peptide Containing an Unprecedented Lysine-to-Tryptophan Crosslink. Nature Chem. 2015, 7, 431-437.
Awards
Eli Lilly-Edward C. Taylor Fellowship in Chemistry (2016)
Hubbel Prize for Best Third Year Seminar (2015)
Pickering Teaching Award (2014)