Brett C. Covington

Ph.D. Chemistry, Vanderbilt University (with Prof. Brian Bachmann)
bc17@princeton.edu

Mo Lab Publications

Covington, B. C.; Xu, F.; Seyedsayamdost, M. R. A Natural Product Chemist’s Guide to Unlocking Silent Biosynthetic Gene Clusters. Annu. Rev. Biochem. 2021, 90, 763-788.

Rued, B. E.; Covington, B. C.; Bushin, L. B.; Szewczyk, G.; Laczkovich, I.; Seyedsayamdost, M. R.; Federle, M. J. Quorum Sensing in Streptococcus mutans Regulates Production of a Novel Class of Antimicrobial Compounds. mBio, 2021, In Press.

Bushin, L. B.; Covington, B. C.; Rued, B. E.; Federle, M. J.; Seyedsayamdost, M. R. Discovery and Biosynthesis of Streptosactin, a Sactipeptide with an Alternative Topology Encoded by Commensal Bacteria in the Human Microbiome. J. Am. Chem. Soc. 2020, 142, 16265-16275.

Yoshimura, A.; Covington, B. C.; Gallant, É.; Zhang, C.; Li, A.; Seyedsayamdost, M. R. Unlocking Cryptic Metabolites with Mass Spectrometry-guided Transposon Mutant Selection. ACS Chem. Biol. 2020, 15, 2766-2774.

Isley, N. A.; Endo, Y.; Wu, Z. C.; Covington, B. C.; Bushin, L. B.; Seyedsayamdost, M. R.; Boger, D. L. Total Synthesis and Stereochemical Assignment of Streptide. J. Am. Chem. Soc. 2019, 141, 17361-17369.