Ph.D. Chemistry, Vanderbilt University (with Prof. Brian Bachmann)
bc17@princeton.edu
Mo Lab Publications
Clark, K. A.; Covington, B. C.; Seyedsayamdost, M. R. 2022, Submitted.
Covington, B. C.; Seyedsayamdost, M. R.Vitamin B3 Triggers Biosynthesis of Secondary Metabolite Dormancy Signals in Streptococcus suis. J. Am. Chem. Soc. 2022, 144, 14997-15001.
Bushin, L. B.; Covington, B. C.; Clark, K. A.; Caruso, A.; Seyedsayamdost, M. R. Bicyclostreptins are Radical SAM Enzyme-modified Peptides with Unique Cyclization Motifs. Nat. Chem. Biol. 2022, In Press.
Seyedsayamdost, M. R.; Covington, B. C.; Zhang, Y.; Li, Y. Natural Product Discovery. Invited Book Chapter Submission: “Advanced Chemical Biology” Edited by Howard Hang, Jennifer Prescher, and Matthew Pratt. Wiley 2022, In Press.
Covington, B. C.; Seyedsayamdost, M. R.Guidelines for Metabolomics-guided Transposon Mutagenesis for Microbial Natural Product Discovery. Methods Enzymol. 2022, 665, 305-323.
Clark, K. A.; Covington, B. C.; Seyedsayamdost, M. R.Biosynthesis-guided Discovery of Enteropeptins, Unusual Sactipeptides Containing an N-Methylornithine. ChemRxiv 2021, DOI: 10.26434/chemrxiv-2021-jnv18.
Covington, B. C.; Seyedsayamdost, M. R. MetEx, a Metabolomics Explorer Application for Natural Product Discovery. ACS Chem. Biol. 2021, 16, In Press.
Covington, B. C.; Xu, F.; Seyedsayamdost, M. R. A Natural Product Chemist’s Guide to Unlocking Silent Biosynthetic Gene Clusters. Annu. Rev. Biochem. 2021, 90, 763-788.
Rued, B. E.; Covington, B. C.; Bushin, L. B.; Szewczyk, G.; Laczkovich, I.; Seyedsayamdost, M. R.; Federle, M. J. Quorum Sensing in Streptococcus mutans Regulates Production of a Novel Class of Antimicrobial Compounds. mBio, 2021, In Press.
Bushin, L. B.; Covington, B. C.; Rued, B. E.; Federle, M. J.; Seyedsayamdost, M. R. Discovery and Biosynthesis of Streptosactin, a Sactipeptide with an Alternative Topology Encoded by Commensal Bacteria in the Human Microbiome. J. Am. Chem. Soc. 2020, 142, 16265-16275.
Yoshimura, A.; Covington, B. C.; Gallant, É.; Zhang, C.; Li, A.; Seyedsayamdost, M. R. Unlocking Cryptic Metabolites with Mass Spectrometry-guided Transposon Mutant Selection. ACS Chem. Biol. 2020, 15, 2766-2774.
Isley, N. A.; Endo, Y.; Wu, Z. C.; Covington, B. C.; Bushin, L. B.; Seyedsayamdost, M. R.; Boger, D. L. Total Synthesis and Stereochemical Assignment of Streptide. J. Am. Chem. Soc. 2019, 141, 17361-17369.